Signatures of Drug Sensitivity in Nonsmall Cell Lung Cancer
نویسندگان
چکیده
منابع مشابه
Signatures of Drug Sensitivity in Nonsmall Cell Lung Cancer
We profiled receptor tyrosine kinase pathway activation and key gene mutations in eight human lung tumor cell lines and 50 human lung tumor tissue samples to define molecular pathways. A panel of eight kinase inhibitors was used to determine whether blocking pathway activation affected the tumor cell growth. The HER1 pathway in HER1 mutant cell lines HCC827 and H1975 were found to be highly act...
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Apatinib is a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor-2, which has been proved to be effective and safe in treating heavily pretreated patients with gastric cancer.The aim of the study was to explore the use of apatinib in treatment of nonsmall cell lung cancer and its side effects.We report 2 patients presented with advanced nonsmall-cell lung canc...
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ژورنال
عنوان ژورنال: International Journal of Proteomics
سال: 2011
ISSN: 2090-2166,2090-2174
DOI: 10.1155/2011/215496